Session guidance
How to be in the session.
Breathing, grounding, body awareness, and safe introspection for Spravato® treatment.
The session is the medicine
Spravato® opens a window. What you do inside that window — how you breathe, where you place your attention, how you hold difficult feelings — shapes what you take away from it.
These aren't rules. They're invitations. Every session is different, and every patient is different. Use what helps. Leave what doesn't.
Before you begin
Cover your eyes
Cover your eyes. An eye mask or folded cloth blocks visual input and helps the mind turn inward. Darkness reduces distraction and deepens the experience.
Use quality headphones
Use quality headphones. Over-ear headphones with good frequency response let you hear the full range of the music — the low rumble, the high shimmer — in a way that earbuds and room speakers simply cannot match. The music is the medicine. Deliver it well.
One more thing before you close your eyes
Go pee first. Seriously. Spravato® has a well-known (and well-documented) way of making your bladder suddenly very opinionated about 20 minutes in. The nurses have seen it a thousand times. Save yourself the interruption — and the very awkward shuffle to the bathroom mid-session — and take care of it before you get settled.
Breathing
Your breath is the most reliable anchor you have during a session. When things feel intense or disorienting, returning to the breath can restore a sense of safety.
- Try box breathing before the session begins: inhale 4 counts, hold 4, exhale 4, hold 4. This activates the parasympathetic nervous system.
- During the session, breathe slowly and naturally. Don't force it — just notice it.
- If anxiety rises, lengthen your exhale. A longer exhale than inhale (e.g. in for 4, out for 6) signals safety to the nervous system.
- Mouth breathing can increase dissociation. Nasal breathing tends to feel more grounding.
Grounding
Grounding techniques help you stay connected to your body and the present moment — especially useful if the experience becomes overwhelming.
- Feel the weight of your body in the chair or bed. Notice the pressure of the surface beneath you.
- Keep your eyes closed or use an eye mask. Reducing visual input often makes the experience feel more contained and safe.
- If you feel lost or frightened, remind yourself: 'This is temporary. I am safe. The medicine will pass.'
- A weighted blanket or soft object to hold can provide physical grounding throughout the session.
Safe introspection
Spravato® can surface difficult emotions, memories, or insights. How you relate to what arises matters as much as what arises.
- Adopt an attitude of curious observation rather than judgment. You are watching, not being consumed.
- If something difficult comes up, try to stay with it rather than pushing it away. Resistance often intensifies the experience.
- You don't need to understand everything in the moment. Let images, feelings, and impressions arise and pass without forcing meaning.
- Trust the process. Many patients find that the most uncomfortable moments yield the most meaningful insights in integration.
Body awareness
During a Spravato® session, sensation is information. Turning attention toward the body — rather than toward thought or language — keeps you in the experience rather than narrating it.
- Notice where you feel the music in your body. Let sensation be your guide rather than thought.
- If emotion arises, locate it physically — tightness in the chest, warmth in the face, heaviness in the limbs. Stay with the sensation rather than the story.
- Avoid reading, scrolling, or any text-based activity during the session. Language engages the analytical mind and works against the medicine.
- Skip guided meditations with spoken words. Verbal instruction pulls you into the language center — the opposite of where Spravato® wants to take you. Let the music guide instead.
After the session
Integration is where the real work happens. The session opens a door — integration is walking through it. Rest, gentle movement, and time in nature in the 24–48 hours after a session can significantly deepen its therapeutic benefit. If you want to capture what arose, wait until you're fully grounded — and draw, sketch, or voice-memo rather than write. Also: you cannot drive for the rest of the day. This isn't a suggestion — it's a federal requirement of the Spravato® REMS program. Arrange a ride before your session, not after.
- Protect your schedule after sessions when possible. Avoid high-stimulation environments, difficult conversations, or major decisions.
- Gentle movement — walking, stretching, yoga — helps the body process what the mind experienced.
- Share what arose with your therapist or prescriber. Integration support is a core part of the treatment.
Music makes the session.
The right playlist can transform a Spravato® session. Explore our curated guides to find music that fits your needs.
Explore the music guidesNow available
The Listening to Spravato® Book
Genre guides, session playlists, and the science of music-assisted healing — by Justin Page