Relaxing Music

Calm the Nervous System First.

Before the medicine can do its deepest work, the body needs to feel safe. Relaxing music creates that container — reducing anxiety, slowing the breath, and signaling to the nervous system that it's okay to let go.

Why Relaxing Music Works

Anxiety during Spravato® sessions is common, especially in early treatments. The right music acts as a co-regulator — its steady, predictable qualities help the nervous system down-regulate. Research in music therapy shows that slow tempos (60–80 BPM), low frequencies, and minimal harmonic tension are most effective for anxiety reduction.

Genres

Best Genres for Relaxation

Ambient / Drone

Slow-evolving textures with no strong rhythmic pulse. Creates a sense of floating and spaciousness. Artists like Brian Eno, Stars of the Lid, and Grouper are excellent starting points.

Tempo: No fixed tempoMood: Spacious, floating, safe

Slow Classical

Adagio movements from Baroque and Romantic composers. The predictable harmonic language feels familiar and safe. Satie, Debussy, and Arvo Pärt are particularly well-suited.

Tempo: 40–70 BPMMood: Gentle, structured, familiar

Nature Soundscapes

Rain, ocean waves, forest sounds — with or without gentle music underneath. Particularly helpful for patients who find pure music overstimulating in early sessions.

Tempo: No tempoMood: Grounding, natural, calming

Tibetan / Crystal Bowls

Sustained tones from singing bowls create a meditative resonance. The overtones are physically calming and help anchor attention in the body.

Tempo: No tempoMood: Meditative, resonant, centering

Recommendations

Artists & Albums to Explore

Brian Eno

Ambient 1: Music for Airports

The gold standard of ambient music. Gentle, non-intrusive, endlessly spacious.

Erik Satie

Gymnopédies & Gnossiennes

Slow, melancholic piano pieces. Familiar enough to feel safe, beautiful enough to move you.

Arvo Pärt

Spiegel im Spiegel

Minimalist piano and violin. Deeply peaceful, almost sacred in quality.

Moby

Long Ambients 1 & 2

Created specifically for sleep and relaxation. Freely available on his website.

Stars of the Lid

And Their Refinement of the Decline

Orchestral ambient. Slow, vast, emotionally open without being overwhelming.

Max Richter

Sleep (Gentle Versions)

Composed to accompany sleep. Extraordinarily gentle and safe.

Practical advice

Listening Tips

1

Start your playlist 5–10 minutes before the medicine takes effect so you're already in a calm state when it begins.

2

Use over-ear headphones if possible. They create a more immersive, contained experience than earbuds or speakers.

3

Set your volume at a comfortable level before the session — you won't want to adjust it once the medicine is active.

4

If you feel anxious during the session, focus on the lowest sounds in the music — bass tones and low drones are particularly grounding.

Now available

The Listening to Spravato® Book

By Justin Page — genre guides, session playlists, and the science of music-assisted healing

Get the Book
Listening to Spravato®

A guide to using sound intentionally during Spravato® treatment — for patients, clinicians, and caregivers seeking deeper healing through music.

Not medical advice. Justin Page is a conservatory-trained musician (Manhattan School of Music; Berklee College of Music), Presidential Scholar, and Spravato® patient who has undergone more than 80 documented esketamine treatment sessions. His work on music and esketamine neuroscience has been reviewed by clinical collaborators and submitted to the treatment manufacturer for feedback and verification. Content on this site reflects personal clinical experience, independent research, and ongoing collaboration with licensed mental health professionals — it does not constitute medical advice and is not a substitute for guidance from your prescriber, therapist, or care team. Always consult your treating clinician before making any changes to your treatment protocol.

© 2026 Listening to Spravato®. All rights reserved.

Spravato® is a registered trademark of Janssen Pharmaceuticals, Inc., which is part of Johnson & Johnson.